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Soloxine®
Tablets
(Levothyroxine
Sodium Tablets)
Levothyroxine sodium acts, as does endogenous thyroxine, to stimulate
metabolism, growth, development and differentiation of tissues.
Levothyroxine sodium is absorbed rapidly from the gastrointestinal
tract after oral administration. Following absorption, the compound
becomes bound to the serum alpha globulin fraction. For purposes
of comparison, 0.1 mg of levothyroxine sodium elicits a clinical
response approximately equal to that produced by one grain (65 mg)
of desiccated thyroid. Soloxine is available in uniquely shaped,
color coded tablets in eight different strengths to allow easy and
convenient dosage adjustment.
Hypothyroidism is the generalized metabolic disease resulting from
deficiency of the thyroid hormones levothyroxine (T4) and liothyronine
(T3). Canine hypothyroidism is usually primary, i.e. due to atrophy
of the thyroid gland. In the majority of cases the atrophy is associated
with lymphocytic thyroiditis and in the remainder it is non-inflammatory
and as of yet unknown etiology. Less than 10 percent of cases of
hypothyroidism are secondary, i.e. due to deficiency of thyroid
stimulating hormone (TSH). TSH deficiency may occur as a component
of congenital hypopituitarism or as an acquired disorder in adult
dogs, in which case it may be due to the growth of a pituitary tumor.
Soloxine provides thyroid replacement therapy in all conditions
of inadequate production of thyroid hormones.
Soloxine (Levothyroxine Sodium Tablets) will provide levothyroxine
(T4) as a substrate for the physiologic deiodination to liothyronine
(T3). Administration of levothyroxine sodium alone will result in
complete physiologic thyroid replacement.
The initial recommended dose is 0.1 mg/10 lb. (4.5 kg) body weight
twice daily. Dosage is then adjusted by monitoring the thyroid blood
levels of the dog every four weeks until an adequate maintenance
dose is established. The usual maintenance dose is 0.1 mg/10 lb.
(4.5 kg) once daily.
Precautions: Administer with caution to animals with clinically
significant heart disease, hypertension, or other complications
for which sharply increased metabolic rate might prove hazardous.
See package insert for contraindications and precautions.
This product must be prescribed by a licensed veterinarian.
People
and Pets - Thyroid Disease (produced
by UCTV)
"Thyroid disease can afflict both humans, dogs, and cats. Hypothyroidism
and hyperthyroidism are discussed. While in the past proper diagnosis
was tricky or even missed, today diagnosis can be straight forward.
Current treatments are also reviewed."
Click on button above to view People and Pets.
Total running time is 3:06 mins.
32 MB mpeg format video file .
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Legal
information
The following information is intended for use only by visitors to this
site located in the United States.Countries outside the United States
may have regulatory, legal requirements or veterinary medical practices
that are different from those in the United States and may require different
or additional information. The use of this information may not be appropriate
for use outside of the United States.
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